Reveal
A Phase 2 Clinical Trial Evaluating AMG 714 Treatment for Vitiligo
Update Clinical Trials as of 05/14/2025
Topical
- A Trial of SHR0302 Base in Patients with Vitiligo
Drug: SHR0302 base gel
- A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects with Non-segmental Vitiligo
Drug: VYN201 1% gel
Drug: Placebo
- A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo
Drug: Ruxolitinib 1.5% Cream
Drug: Placebo
- Daily Topical Rapamycin for Vitiligo
Drug: Topical 0.1% or 0.001% rapamycin
Drug: Vehicle
- Topical 5-Fluorouracil Effervescent Powder in the Treatment of Vitiligo
Drug: Topical 5-Fluorouracil Effervescent Powder
Drug: Topical 5-Fluorouracil Plain Powder
- Stude of Efficacy, Safety, and Tolerability of Crisaborole and PF-07038124 With and Without NBUVB in Vitiligo
Drug: Topical Crisaborole 2% Ointment + NBUVB
Systemic
- Vitiligo, New Treatment and Serum s100B
Drug: Baricitinib + NBUVB phototherapy
Drug: Oral mini pulse steroids + NBUVB phototherapy
- A Study to Evaluate the Efficacy and Safety of SYHX1901 Tablet in Non-segmental Vitiligo Patients
Drug: SYHX1901
Drug: Placebo
- Evaluation of AMG 714 for Vitiligo (REVEAL)
Drug: AMG 714 (Anti-IL-15 monoclonal antibody)
Drug: Placebo
- A Study To Assess Adverse Events and Effectiveness of Upadacitinib Oral Tablets in Adult and Adolescent Participants With Vitiligo (Viti-Up)
Drug: Upadacitnib + NBUVB Phototherapy
Drug: Placebo + NBUVB Phototherapy
Drug: Ritlecitinib
Drug: Placebo
- Evaluating the Efficacy and Safety of Metformin in Vitiligo
Drug: Metformin Hydrochloride
- Efficacy and Tolerance of the Association of ANIFROLUMAB (300mg) IV Every Four Weeks and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo (VITANI)
Drug: Anifrolumab + NBUVB PHOTOTHERAPY
Drug: Placebo + NBUVB PHOTOTHERAPY
- ERASE VITILIGO Early Repigmentation Approach for Stopping the Evolution of VITILIGO Prospective Multicentric Interventional Study With Blinded Evaluation (ERASE)
Drug: Oral mini pulse (OMP) steroids + NBUVB PHOTOTHERAPY
- Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo (METVI)
Drug: Methotrexate + NBUVB phototherapy
Drug: Placebo + NBUVB phototherapy
- A Study to Compare the Efficacy and Safety of SCENESSE and Narrow-Band Ultraviolet (NB-UVB) Light Versus NB-UVB Light Alone in Patients With Vitiligo
Drugs: Afamelanotide + NBUVB Phototherapy
Device: NBUVB Phototherapy
- A Study to Assess the Changes in Pigmentation and Safety of Afamelanotide in Patients With Vitiligo on the Face
Drug: Afamelanotide
- Vitiligo Treatment by Targeting TYK2 Mediated Responses (ViTYK)
Drug: Deucravacitinib
Drug: Placebo
Drug: Deucravacitinib + NBUVB Phototherapy
- A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V2)
Drug: Povorcitinib
Drug: Placebo
- A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)
Drug: Povorcitinib
Drug: Placebo
- A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2 (Tranquillo 2)
Drug: Ritlecitinib (50 mg vs. 100 mg)
Drug: Placebo
- A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) Tranquillo (Tranquillo)
Drug: Ritlecitinib (50mg)
Drug: Placebo
- A Clinical Study of MK-6194 for the Treatment of Vitiligo (MK-6194-007)
Drug: MK-6194
Drug: Placebo
Additional References:
Pilot Study Assessing the Effect of Tildrakizumab in Vitiligo (TILDVIT-1227)
Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation
Procedural
- Comparison Between Systemic Steroids, Topical Steroids, or Calcineurin Inhibitors With Mini Punch Grafting in Treatment of Stable Non-segmental Vitiligo
Intervention: Oral steroids with punch grafting
Intervention: Topical steroids or calcineurin inhibitors with punch grafting
Intervention: Punch grafting
- Improved Phototherapy in Patients with Vitiligo
Procedure: Peri-lesional NBUVB Phototherapy
Procedure: Lesional NBUVB Phototherapy
Additional Resources:
Enhanced Transcutaneous Delivery of Betamethasone for the Treatment of Vitiligo
Mechanisms of Action of Photo(Chemo)Therapy in Skin Diseases (BioUV2017)
Other
- Deciphering the Vitiligo Transcriptomic Signature Between Repigmented and Non Repigmented Lesions (STRAVI)
Diagnostic Test: Skin and blood samples
Diagnostic Tests: Saliva, skin, and blood sample
- Translational Assessment of Vitiligo According to Body Locations (Vitiligo BL)
Diagnostic Test: skin biopsy
- A Prospective, Observational Study of Clinician and Patient-reported Outcomes in Patients With Dermatological Conditions
Study design: Observational study
Study Design: Observational study
Study Design: Observational Study
- A Pilot Cohort Study of Risk Factors and Novel Methods of Skin Lesion Assessments in Adults With Atopic Dermatitis, Alopecia Areata, Psoriasis or Vitiligo (Derma-001)
Study Design: Observational Study
- A Single-Site Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
Study Design: Observational Study
- Measure of Acceptance of chRonic Visible sKin conditionS (MARKS)
Study Design: Observational Study