Julien Seneschal, MD, PhD
Professeur Julien Seneschal
Department of Dermatology, Auto-immune and Inflammatory Skin Diseases Unit
National Reference Centre for Rare Skin Diseases
INSERM U0135, Immuns-Dermatology Team
University of Bordeaux, France
Vitiligo: Looking at the Memory T Cell Response
While vitiligo is associated with complex and combinatorial immune factors, one immune cell subset, called resident memory T cells received particular attention over the past year. This T cell subset display a memory phenotype, have a distinct transcriptional program and express characteristic cell surface markers, with a major role in vitiligo pathogenesis. Indeed; their role could explain the recurrence of the disease on previously affected anatomic sites. This talk will summarize current knowledge about resident memory T cells in vitiligo.